Proportion

Pills or oral medications contain inactive ingredients such as gluten that may be responsible for dangerous side effects, concludes a new study. The research appeared in the latest issue of the journal Science Translational Medicine.

The researchers explain that the allergic reactions to the pills may be due to inactive ingredients that make up the pill including lactose, gluten, food dyes etc. People who are allergic to these ingredients may experience worsening of their symptoms or allergic reactions.

Dr. Giovanni Traverso, from the department of gastroenterology at Brigham and Women’s Hospital and Harvard Medical School said that the results were surprising to the team of researchers. He was one of the authors of the study. He added, “. It involves almost every pill and capsule. And it’s something we tend not to think about.”

Traverso is also part of the mechanical engineering department at MIT. He explained that the idea for this study came after a patient of Celiac disease presented with worsening of symptoms. The patient was not aware that the medication contained gluten, Traverso said and none of the prescribers were either.

The team looked at other patients who had experienced similar side effects after taking the medication and found that several drug preparations could be harmful because of these seemingly innocuous ingredients.

In 2017, the Food and Drugs Administration had prepared draft recommendations to label drug formulations that contained wheat derived products. The FDA also has a database with the list of all the inactive ingredients in prescription drugs.

For most patients, it doesn’t matter if there’s a little bit of lactose, a little bit of fructose, or some starch in there. However, there is a subpopulation of patients, currently of unknown size, that will be extremely sensitive to those and develop symptoms triggered by the inactive ingredients.”

Daniel Reker, Lead Author

The team found that 44.82 percent of the pills contain lactose which can cause side effects among those who are lactose intolerant. Similarly 33 percent of the preparations contain food dyes. Around 3.8 percent of a study population was found to be allergic to a food dye called tartrazine.

Related Post

Leave a comment

Your email address will not be published. Required fields are marked *